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So when astronauts start spinning, it's even more aboard the ISS. These targets have changed in their vision. For example, they found that as their mission went on, they needed stronger, stronger machine glasses. And researchers, studying this development, found swelling in the optic disc. This is where the optical curvature ran up. In the center of the eye shape, in these centers became an open space associated with oral ocular syndrome, or SAM, short.