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And then you end up with the ligaments that are just the amyloids that haven't clumped together yet. And neurofibrillary tangles, and these are just abnormal clumps of cow proteins, and that, these clumps, once the cows start breaking off the axons and start moving away further into neurons, that's when they start causing a lot of issues with the signaling function of the neuron. So amyloid Bs, amyloid Bs are toxic, and one of that, the amyloid B processes, gives rise to a lot of processes that happen after that. So on to the research.